Synergism among BIOLF-62, phosphonoformate, and other antiherpetic compounds.

نویسندگان

  • K O Smith
  • K S Galloway
  • K K Ogilvie
  • U O Cheriyan
چکیده

9-[[2-Hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine (BIOLF-62) is highly synergistic with either phosphonoformate or phosphonoacetate when used in combination against herpes simplex virus types 1 and 2 in vitro. Acycloguanosine did not show significant synergism with these two compounds. Bromovinyldeoxyuridine and phosphonoformate were highly synergistic against herpes simplex virus type 2, but not against type 1.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 22 6  شماره 

صفحات  -

تاریخ انتشار 1982